MAP kinase-activated protein kinase 2 (MAPKAPK2) is an enzyme that in humans is encoded by the MAPKAPK2 gene.It was discovered that MAPKAP kinase-2 (MK2) phosphorylates glycogen synthase at serine-7 and the serine in a peptide (GS peptide-1) designed to mimic the N-terminus of glycogen synthase.
A novel protein kinase called MAPKAP kinase-2 is triggered by mitogen-activated protein kinase. This MAPKAP kinase-2, also known as MAP kinase activated protein kinase-2, differs from S6 kinase-II (MAPKAP kinase-1) by how it reacts to inhibitors, the fact that it doesn't phosphorylate S6 peptides, and its amino acid sequence.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V2340 | MK2 Inhibitor III | 724711-21-1 | MK2-IN-3 is a potent and selective MAPKAP-K2 (MK-2) inhibitor with an IC50 value of 8.5 nM. |
|
V4323 | MK2-IN-1 | 1314118-92-7 | MK2-IN-1 is a novel, potent,non-ATP competitive and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM). |
|
V4322 | MK2-IN-1 HCL | 1314118-94-9 | MK2-IN-1 HCl is a novel, potent, non-ATP competitive and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM). |
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